Saturday, December 31, 2011

Ohio State quarterback may keep Florida busy in Gator Bowl

Ohio State quarterback may keep Florida busy in Gator Bowl

When new head coach Urban Meyer starts putting his Ohio State football team through its first spring drills, one of the first things that will almost certainly bring a smile to his face with be

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Source: http://www.news-press.com/article/20111231/SPORTS/312310036/1010/SPORTS

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Friday, December 30, 2011

Wendale Davis Foundation basketball tournament to benefit community

The Wendale Davis Foundation, 1330 3rd St., is hosting its second annual basketball tournament?Tuesday and Wednesday?at Stonecreek Jr. High School, 8000 Akers Road.

The tournament will showcase the talented young people in our community. Games start at 8 a.m. Wednesday.

Admission is $3 per person.?If you bring a canned food item you will receive $1 off the price of admission.?Canned food donations will be used to benefit the community.

Source: http://southeast.bakersfieldnow.com/news/community-spirit/72879-wendale-davis-foundation-basketball-tournament-benefit-community

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Thursday, December 29, 2011

BC-FBN--Jones-Drew-Concussions,1st Ld-Writethru, FBN

BC-FBN--Jones-Drew-Concussions, 1st Ld-Writethru,603Jones-Drew: Suits fuel NFL's concussion changesAP Photo NY154, JVS202Eds: Updates with details, quotes. With AP Photos.By MARK LONGAP Sports Writer

JACKSONVILLE, Fla. (AP) ? Jacksonville Jaguars running back Maurice Jones-Drew wonders how much of the NFL's efforts to prevent or properly treat concussions have to do with lawsuits brought by former players against the league and its teams.

The NFL's leading rusher spoke out about the issue again Wednesday, nearly a week after telling The Associated Press he would hide a possible head injury so he could stay in a game.

"I've had concussions before, and it wasn't this big deal about concussions," Jones-Drew said. "The only reason they're making a big deal about concussions right now is because the league is getting sued over it. Before this, you never heard about it. A couple of years ago, you didn't hear anything about it."

After NFL Commissioner Roger Goodell was grilled about his sport's concussion policies at a congressional hearing in October 2009, the league made several significant changes. Those moves have continued, including this month's addition of certified athletic trainers sitting in booths during games to keep an eye out for possible head injuries and alert teams' medical staffs.

Starting this summer, at least eight lawsuits have been filed against the NFL by dozens of retired players who say they have medical problems related to brain injuries from their time in professional football. The NFL's stance, in part, is that players knew there were risks of injury, and there was no misconduct or liability on the league's part.

Jones-Drew called the possibility of serious injury in football an "occupational hazard."

He was one of 44 players the AP interviewed recently about concussions. Slightly more than half ? 23 ? said they would try to hide a concussion and stay in a game rather than pull themselves out.

Players generally indicated they are more aware now of the possible long-term effects of jarring hits to the helmet. Five said that while they would have tried to conceal a concussion during a game in 2009, now they would seek help.

Players also said they should be better protected from their own instincts: More than two-thirds of the group the AP talked to would like to have independent neurologists on sidelines during games.

"You know playing football you're going to get hurt, right?" Jones-Drew said Wednesday. "In the back of your mind, you've got to know that the worst that can happen is you can break your neck and be paralyzed for the rest of your life, right? You have to go into every game knowing that could be what happens. Any given play that could happen to you, right? So there it is. When you sign these deals, you know in the back of your mind, that's what can happen.

"Now basketball, on the other hand, it's a different sport. Race car driving, you know that when you get in that car, there can be an opportunity for that thing to flip over and catch on fire. You see what I'm saying? It's an occupational hazard, simple as that, and you have to be willing to accept it, and I am."

Jones-Drew reiterated that he takes the risk because of his family and said he strongly believes NFL teams would be hesitant to sign players with a history of concussions. So he would hide a concussion to stay in a game, even if it meant increased potential for long-term health issues.

''I would do anything for my kids," he said. "If they're happy, I'm happy. I think they would appreciate it. As long as my kids' kids would be happy with what I did, that's what this life is about: sacrifice. It's not about you anymore, you know?"

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2011-12-28-Jones-Drew-Concussions/id-39d77942c624417d8f6179e011f16476

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Consumer confidence hits 8-month high in December (Reuters)

WASHINGTON (Reuters) ? Consumer confidence rose more than expected in December, hitting an eight-month high, as Americans grew more upbeat about the labor market and their financial situation.

The Conference Board, an industry group, said its index of consumer sentiment increased to 64.5 from a downwardly revised 55.2 in November.

Economists had expected a reading of 58.3 from a previously reported 56.0 in November.

The rise in sentiment offered hope for a pick-up in consumer spending after a tepid performance in November.

Labor market conditions have improved in recent months, with the unemployment rate falling to a 2-1/2 year low in November and applications for first time jobless benefits at the lowest since April 2008.

The survey's present situation index rose to 46.7 this month --- the highest since September 2008 -- from 38.3 in November. The expectations index surged to 76.4 from 66.4 in November.

"Consumers are more optimistic that business conditions, employment prospects and their financial situations will get better," the Conference Board said in a statement.

"While consumers are ending the year in a somewhat more upbeat mood, it is too soon to tell if this is a rebound from earlier declines or a sustainable shift in attitudes."

(Reporting By Lucia Mutikani; Editing by Kenneth Barry)

Source: http://us.rd.yahoo.com/dailynews/rss/economy/*http%3A//news.yahoo.com/s/nm/20111227/bs_nm/us_usa_economy_confidence

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Wednesday, December 28, 2011

HTC Super Tool Unlocks and Roots Many Popular HTC Devices [Android Rooting]

HTC Super Tool Unlocks and Roots Many Popular HTC DevicesOwners of popular HTC phones like an Evo, myTouch, G2, and others can now root their phone in just a few simple steps with the HTC Super Tool for Windows.

The tool uses the popular zergRush exploit, which works on a number of HTC phones and can be found in other tools like previously mentioned Revolutionary. With just a few clicks, you can root your phone, get S-OFF, unlock the bootloader, get rid of Sense, and more. You can even unroot by re-running the program. Right now, the device has been tested on the Evo Design 4G, Evo 4G, Evo 3D, Evo Shift, T-Mobile G2, myTouch 3G and 4G, Inspire, Sensation, Incredible, Wildfire S, and Amaze, though it should work on a number more. If you test it with your phone and find that it works, let the developer know over at XDA, and email me at whitson+rootingguide@lifehacker.com so I can add it to the list. We'll be adding this method to our always up-to-date rooting guide as well very soon. Hit the link to check it out.

HTC Super Tool | XDA Developers via Android and Me

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/FGPW-6BRNGg/htc-super-tool-unlocks-and-roots-many-popular-htc-devices

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Tuesday, December 27, 2011

13 found dead in truck in eastern Mexico: local media (Reuters)

MEXICO CITY (Reuters) ? Thirteen bodies were found in an abandoned truck in eastern Mexico on Sunday, local media reported, as a turf war between drug cartels spreads far from the border with the United States.

The truck was found during a routine security patrol near the border between the eastern states of Veracruz, a major oil-producing region, and Tamaulipas, local media said, citing state officials.

Messages left at the site suggested the dead were killed in a rivalry between criminal gangs, local media said.

Violent drug cartels that have long menaced Mexico's northern border with the United States have moved into states like Veracruz as they battle rivals for control of drug routes and other criminality.

On Thursday, three American citizens were killed in Veracruz when gunmen attacked the bus in which they were traveling.

On Friday, the tortured bodies of ten people were found in Veracruz as a turf war between the Zetas gang and Gulf drug cartels intensifies.

In September, 35 bodies were dumped along a downtown highway in the Veracruz city of Boca del Rio.

More than 45,000 people have been killed in drug violence since President Felipe Calderon took office in December 2006. (Reporting by Patrick Rucker; editing by Todd Eastham)

Source: http://us.rd.yahoo.com/dailynews/rss/mexico/*http%3A//news.yahoo.com/s/nm/20111226/wl_nm/us_mexico_dead

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Chinese Message Boards Warn Citizens of Stairs that Look Like Escalator; Number of Embarrassed Shoppers Expected to Reach the Hundred Thousands

Every once in a while I come across an escalator that seems out of order. But upon taking my first disappointed step to walk up, the elevator gently shakes to life and carries me triumphantly the rest of the way thinking ?How do they know??

With an increasing effort to conserve energy these escalators are becoming more prevalent and bringing us one step closer to life as seen on The Jetsons.

It?s been said that ?half the joy in life is in the little things taken on the run? like these magical machines. However, the same could also be said about half the agony. A case in point are the steps featured in this photograph that has been circulating around Chinese message boards and drawing the ire of many embarrassed shoppers.

Looking at the picture, it?s understandable how people can mistake this plain flight of stairs for an energy saving escalator. Imagine wandering through the shopping mall with bags in each arm, checking your mobile phone while thinking about what to eat in the food court when you see that familiar black rubber railing. Once you climb onto the step, there is an excruciatingly long second until you realize you?re not moving anywhere. It?s just enough time for anyone in a 10m radius to immediately size you up as mentally challenged.

On the topic of embarrassing situations involving steps, have you ever tried walking up a non-functioning escalator? Even though you can normally manage a staircase like one of those parkour guys, when you have to walk up an escalator that isn?t moving you suddenly feel like a drunk three-year old. This is caused by a combination of our expectation of escalators to move and the phenomenon of ?peripheral drift illusion?. This is where indirectly seeing two strongly contrasting shades (for example, the yellow safety stripes against the black steps) trick our brains into thinking something?s moving when it isn?t. So whenever taking an escalator, be sure to watch your step? then again maybe you shouldn?t.

Source:tt.mop.com?chaina?
[ Read Japanese version ]

Source: http://feeds.rocketnews24.com/~r/rocketnews24/en/~3/H3W0XcHawtE/

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Monday, December 26, 2011

Royals to visit UK's Prince Philip after heart surgery (Reuters)

LONDON (Reuters) ? Queen Elizabeth's 90-year-old husband Prince Philip had a "good night" after being rushed to hospital for heart surgery and will be visited by members of Britain's royal family on Saturday, Buckingham Palace said.

Britain's longest-serving royal consort, known for his outspoken and sometimes brusque manner, needed an operation to fit a small tube to clear a blocked artery after suffering chest pains as the royal family prepared to celebrate Christmas.

"The Duke of Edinburgh had a good night," a spokeswoman for Buckingham Palace said. "There is an expectation that some of the royal family will visit this morning."

Philip had been due to spend Christmas with members of the royal family - including grandson Prince William and his wife Catherine, accordingly to British media - at the Sandringham royal estate in eastern England, but he may have to spend the holiday in a hospital bed.

Philip, who married Elizabeth in 1947, was taken to Papworth Hospital, one of Britain's main heart and chest centers, about 60 miles away in Cambridge on Friday.

"The Duke of Edinburgh was found to have a blocked coronary artery which caused his chest pains," the palace said. "This was treated successfully by the minimally invasive procedure of coronary stenting."

He would stay in hospital "for a short period" under observation, it added.

The hospital declined to comment although, with members of the royal family visiting him on Saturday, it appeared unlikely he would be discharged until at least Christmas Day.

Philip had attended a lunch for staff a week ago and had been on "very good form," the BBC reported.

"He has had these chest pains before and I don't think it's anything untoward, but given his age they are being safe rather than sorry," former royal press spokesman Dickie Arbiter said.

Despite his age, Philip generally has been in good health and has continued a busy round of charity work and social engagements, recently visiting Australia and Ireland.

A pivotal figure in the House of Windsor, Philip has a reputation as a fiercely loyal consort who prefers outdoor pursuits to introspection.

Britain's tabloid newspapers have delighted over the years in recounting his many public gaffes.

He once told British students in China: "If you stay here much longer, you'll be slitty-eyed."

Born on the Greek island of Corfu in 1921, Philip served in Britain's Royal Navy before marrying Elizabeth. They have four children, including the heir to the throne, Charles.

(Reporting by Matt Falloon and Peter Griffiths; Editing by Alison Williams)

Source: http://us.rd.yahoo.com/dailynews/rss/world/*http%3A//news.yahoo.com/s/nm/20111224/wl_nm/us_britain_royal_philip

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New Canadians know more about Canada than those born here: Survey

',
container = $('#drop-panel-container'),
contents = $(container).html();

if (isIE8) {

$(container).replaceWith(f+contents+b)

}



}

function dropPanelSetUp(data) {
/* buttons should be a dataobject of strings representing IDs
the hide and show functions are expecting IDs so passing a class will result in a
failure.

click as the action is assumed for now

the data object should look like this:

{ masterlistener:(string[dom id]),
panel:(string[dom id]),
eventgroup1:{ button:(string[dom id]),
content:(string[dom id]),
offset:{x:(int),y:(int)},
on_state_class: ''(string)
},
eventgroup2:{ button:(string[dom id]),
content:(string[dom id]),
offset:{x:(int),y:(int)},
on_state_class: ''(string)
} ... etc
}

The drop panel nodes should be placed so they share the same offset parent as the buttons that activate it.

NOTE: IE8 Got-chya: the ID for the panel is hard coded into the IE8 rouned corners code.
If you have changed the ID for the drop panel and are having trouble with IE8
change the ID in the template string in this function: ie8DropPanel()

*/



var speed = 300,
panel = $('#'+data.panel),
buttons = [];



for (var i=1,eg; eg=data[('eventgroup'+i)]; i++) {

var bp = $('#'+eg.button).position(), //button position
ph = $('#'+eg.button).height(), //button height
panelPos = [bp.top+ph, bp.left, eg.offset];
on_state_class = eg.on_state_class;

buttons.push([$('#'+eg.button),$('#'+eg.content),panelPos,eg.button,on_state_class]);

}



$('#'+data.masterlistener).bind('click',{speed:speed,panel:panel,buttons:buttons},function(event){

var org = event.target,
speed = event.data.speed,
panel = event.data.panel,
buttons = event.data.buttons,
panel_open = isPanelOpen(panel);




for (var i=buttons.length-1, b; b=buttons[i]; i--) {
/*
* b[0] = button DOM object
* b[1] = content DOM object
* b[2] = the display co-ord object:
* [0] = top (int)
* [1] = left (int)
* [2] = offset object
* {x,y}(int,int)
* b[3] = button ID (string)
* b[4] = button 'on' class
*/

var button_id = b[3],
same_content = isSameContent(panel,b[1]);

if ( $(org).attr('id') === button_id || $(org).parents('#'+button_id).attr('id')){

if(!same_content) {

hideAllContent(buttons);
movePanel(panel,b[2]);

if (panel_open) {

showContent(b[1],b[0],b[4]);

} else {

showContent(b[1],b[0],b[4]);
showPanel(panel,speed);

}

} else {

hidePanel(panel,speed,b[4]);

}

}

}

function isPanelOpen(panel) {


return ($(panel).css('display').toLowerCase() === 'block');
}

function isSameContent (panel,content) {

return ($(content, panel).css('display').toLowerCase() === 'block');

}

function movePanel(panel,b) {
// b[0] top, b[1] left, b[2] {x,y}

$(panel).css({
'top': (b[0] + b[2].x)
});
$(panel).css({
'left': (b[1] + b[2].y)
});

}

function showPanel(panel,speed) {

$(panel).slideDown(speed);
}

function hidePanel(panel,speed) {

$(panel).slideUp(speed, function() {hideAllContent(buttons);});


}

function showContent(content, button, btn_class) {
$(content).show();
$(button).addClass(btn_class);
}

function hideContent(content) {

$(content).hide();

}

function hideAllContent(buttons) {

for (var i = buttons.length-1, b; b=buttons[i]; i--) {
$(b[1]).hide();
$(b[0]).removeClass(b[4]);
}

}


})


}


return {

ieRoundedCorners:ieRoundedCorners,
ie8DropPanel:ie8DropPanel,
dropPanelSetUp:dropPanelSetUp
}



})();



var headerNavication = (function($,cw) {

var nav_item_list = $('.cw-header .main-nav ul.main > li'),
channel_id_list = '',
channel,
sub_channel;

var findChannel = function () {

var winloc = isIE ? document.URL.split('/') : document.documentURI.split('/') ,
channel_id = winloc[3],
sub_chanel_id = winloc.length > 5 ? '/'+winloc[4]+'/' : '',
reg_sub_find_id = new RegExp(sub_chanel_id,'ig'),
reg_removed_id = /^nav-/i;


for (var i=nav_item_list.length-1,n; n=nav_item_list[i]; i--) {

if ( channel_id === $(n).children('a').attr('id').replace(reg_removed_id,'') ) {
var list = $(n).children('ul').children('li');

if (sub_chanel_id.length > 0) {

for (var j=list.length-1,l; l=list[j]; j--) {

if (reg_sub_find_id.test($(l).children('a').attr('href'))) {
break;
} else {
l = false;
}

}

}

break;

}

}

findChannel = function () {
return [n,l];
}

return [n,l];

}

var init = (function() {
channel = findChannel()[0] || nav_item_list[0];
sub_channel = findChannel()[1];

if (sub_channel) {
highlightSubChannel();
}

clearNav();

if(isIE) {

cw.ieRoundedCorners();

if(isIE8) {
cw.ie8DropPanel();
}
}

if ($('#handle-header').attr('id')) {
cw.dropPanelSetUp({
masterlistener: 'handle-header',
panel: ('drop-panel-container'),
eventgroup1: {
button: 'btn-newspapers',
content: 'panel-newspapers',
offset: {
x: 5,
y: 0
},
on_state_class: 'newspapers-dropdown-on'
},
eventgroup2: {
button: 'btn-networks',
content: 'panel-networks',
offset: {
x: 5,
y: 0
},
on_state_class: 'networks-dropdown-on'
}
});
}

//need to check state of search radio buttons since firefox doesn't reset to the default checked radio button
if($('.cw-header #radio-btn-yp:checked').attr('id') != null){
$('.cw-header #header-search-form').attr('action','http://canadacom.yellowpages.ca/search/');
$('.cw-header #header-search-string').attr('name','what');
$('.cw-header #radio-btn-yp').siblings('label').removeClass('selected');
$('.cw-header #radio-btn-yp').next().addClass('selected');
}

eventSetUp();

}())


function highlightSubChannel() {

if((document.location+"").indexOf("/sports/football/cfl/") > -1) $(".mainnav-item .cfl").addClass('sub-nav-highlight');
else if((document.location+"").indexOf("/sports/football/grey-cup-2011/") > -1) $(".mainnav-item .cfl").addClass('sub-nav-highlight');
else if((document.location+"").indexOf("/sports/football/nfl/") > -1) $(".mainnav-item .nfl").addClass('sub-nav-highlight');
else $(sub_channel).addClass('sub-nav-highlight');
}

function clearNav() {

clearTabs();
$(channel).children('ul').show();
$(channel).css('background-position', 'bottom right');

}

function eventSetUp() {


$('.cw-header .main-nav ').bind('mouseleave', function(event){

if (isIE) {

if ($(event.relatedTarget).parents('.main-nav').length 0)?"" + value.substring(0,pos) + "" + value.substring(pos, term.length) + "" + value.substring(pos + term.length) + "":value.substring(0, term.length) + "" + value.substring(pos + term.length) + ""; }, scroll: false, selectFirst: false }); });

Source: http://feeds.canada.com/~r/canwest/F56/~3/TXg6hwRo3WA/story.html

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Sunday, December 25, 2011

First lady helps track Santa on Christmas Eve (CNN)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS and RSS Feed via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/179036554?client_source=feed&format=rss

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HP Plugs Security Hole With LaserJet Firmware Update, Says No Record Of Printers Set Ablaze By Hackers

laserjetRemember when researchers said a security vulnerability could allow hackers to remotely take over Hewlett-Packard LaserJet printers and even cause them to burst into flames? Fun times, for sure. Of course, HP was quick to point out that the researchers had it all wrong, lamented the "sensational and inaccurate reporting" surrounding the supposed security flaw and said not a single customer had reported any instances of unauthorized access to its LaserJet printers.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/FsdDZ-A8f2o/

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Saturday, December 24, 2011

Manhattan Scientifics Leads with Magnetic Nano-Particle-Based Early Cancer Detection Technology

By Cameron Chai

Manhattan Scientifics is a company specializing in the technology transition and commercialization of nanomedicine technologies that includes the early detection technology of Flynn.

Flynn has spent a decade for fine tuning his early detection technology that is capable of detecting cancerous tumor much earlier with 100% specificity and without radiation when compared to the current mammogram technologies. The technology utilizes iron oxide nanoparticles, which are bonded to the breast cancer antibodies capable of attaching only with breast cancer cells. A SQUID machine is used to detect the magnetic signal released by the bound nanoparticles. The patented technology allows the technician to detect the cancerous tumor having as low as 100,000 cells, whereas a typical mammogram can detect a tumor only when it is having 100 million cells or more.

The article has also noted that the MD Anderson Cancer Center located in Houston has shown interest as a means of recognition of the early detection capability of Flynn?s technology. The article also pointed out the statement of John Hazle of the MD Anderson Cancer Center. According to the statement, the center inked a pre-clinical assessment study of the magnetic nano-particle technology in August 2011.

Source: http://www.mhtx.com/

Source: http://www.azonano.com/news.aspx?newsID=24012

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Christmas cosmonauts: American, Russian, and Dutchman bound for ISS

NASA astronaut Don Pettit, Russian cosmonaut Oleg Kononenko, and Dutch astronaut Andre Kuipers plan to do 57 experiments during five months on the International Space Stations.

Three spaceflyers blasted off today (Dec. 21) from snowy Kazakhstan to spend the holidays on the International Space Station.

Skip to next paragraph

NASA astronaut Don Pettit, Russian cosmonaut Oleg Kononenko, and Dutch astronaut Andre Kuipers, part of the European Space Agency (ESA), lifted off atop the Russian Soyuz TMA-03M spacecraft from Baikonur Cosmodrome in Kazakhstan at 8:16 a.m. EST (1316 GMT).

The trio is bound for the space station, where they are scheduled to dock on Friday (Dec. 23) at 10:22 a.m. EST (1522 GMT). They are set to begin a roughly five-month stay on the orbiting outpost as part of the station's Expedition 30 mission, and will return in May 2012.

RECOMMENDED: Are you scientifically literate? Take the quiz.

ettit, Kononenko and Kuipers will join the three spaceflyers already on the station: commander Daniel Burbank of NASA and flight engineers Anton Shkaplerov and Anatoly Ivanishin of Russia. Their arrival will beef up the station's crew complement to its full six members.

Holiday celebrations

The new arrivals will find the space laboratory festive for the holidays. The current crew has put up holiday decorations to mark the season, and Burbank sent a holiday greeting video down to the people of Earth. [Space Station Commander Sends Holiday Greetings to Earth]

"We'll celebrate the holidays in great fashion after they get here," Burbank said of the new crewmembers. "We've already put up decorations, and we've gathered together all the cards and gifts that our friends and families have sent to us, and we're planning a couple of big meals. That'll be great."

Pettit, Kononenko and Kuipers, each veteran spaceflyers who've been to the space station before, will also have their work cut out for them once they arrive at their new home-away-from-home. In addition to wide-ranging scientific research projects, the crewmembers will spend their time keeping up the station and fixing anything that might break.

"If liquid's squirting out someplace then it's like I'm a plumber for the day; if an electronics box isn't working right then you're an electrical repairman for the day," Pettit said during a press conference a few months before the launch. "You have to remember that the space station is so complicated, no one person could keep all the details in your mind. That's why we need all the folks on the ground."

The presence of six crewmembers onboard the station will allow each spaceflyer to dig deep into research.

"I think I have something like 57 experiments from NASA, from ESA and also from JAXA," the Japan Aerospace Exploration Agency, Kuipers said in a press conference earlier this year. "There's a whole bunch of experiments that I'm looking forward to, experiments in different fields ? fluid physiology, fluid physics."

Source: http://rss.csmonitor.com/~r/feeds/science/~3/ItoU3vLTmdY/Christmas-cosmonauts-American-Russian-and-Dutchman-bound-for-ISS

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Friday, December 23, 2011

Video: First Read Minute

NBC's Mark Murray and Domenico Montanaro discuss the continuing debate in Congress over the payroll tax cut extension, Ron Paul?s rise in Iowa polls, and Chuck Todd?s interview with Mitt Romney.

Related Links:

http://twitter.com/nbcnightlynews

Source: http://video.msnbc.msn.com/nightly-news/45752154/

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thenick700: @CKRapp Spring training is awesome. Whoever thought up baseball + beach was a genius.

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Source: http://twitter.com/thenick700/statuses/149943241742090240

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Monday, December 19, 2011

Romney warms up tepid South Carolina campaign (Reuters)

GREENVILLE, South Carolina (Reuters) ? Republican presidential candidate Mitt Romney warmed up his tepid campaign in South Carolina on Friday with the endorsement of Republican Governor Nikki Haley, winning a key ally for a tough fight.

"We've been hoping for this for a long, long time," Romney said at a campaign event in Greenville with the Tea Party champion Haley standing at his side as he started a two-day tour of the early-voting state.

Romney has been lagging in South Carolina and his backers in the state have been urging him to campaign here more frequently to compete with rival Newt Gingrich, who has been leading in polls of the state's Republicans.

The state is critical on the political calendar. South Carolina holds the first primary in the South on January 21, the third contest, following Iowa on January 3 and New Hampshire on January 10.

While Romney is favored to win New Hampshire, it would be a nightmare scenario for him to lose both Iowa and South Carolina with the winner likely to have important momentum going into the January 31 primary in Florida, which could crown the ultimate nominee.

Romney has had difficulty in appealing to conservatives, particularly those who make up the lion's share of the Republican community in South Carolina. Haley could prove to be a valuable ally.

Haley, an Indian-American, was elected in 2010 as South Carolina's first female governor with the strong backing of Tea Party champion Sarah Palin. Though her popularity has sagged a bit in recent months, her endorsement was still coveted by Republican presidential candidates.

Haley told reporters she believes a spirited campaign of appearances and TV ads would turn around Romney's fortunes in the state. She said South Carolina voters are not concerned about Romney's Mormon religion.

"When it comes to Mormon faith, I will tell you that whatever the person's faith, that's not going to be an issue for my constituents, and the reason I know why is because South Carolina just elected a 38-year old Indian female governor," she said.

She told the crowd she settled on Romney after listening to all the contenders and determining he had the best qualities to be president, including her No. 1 priority: "I didn't want anyone tied to Washington."

Romney, who had campaigned for Haley when she won a come-from-behind victory as governor in 2010, said he hoped to emulate Haley's come-from-behind performance in South Carolina.

"I see every state as a battlefield," Romney said. "There's no place I can look at and say, 'this is going to be easy, I don't need to worry about that.'"

After days of hurling sharp attacks at chief rival Gingrich, Romney renewed his focus again on Democratic President Barack Obama and his leadership of the U.S. economy.

"This is a failed presidency," he said.

Democrats were eager to return fire, seizing on a comment Romney made earlier in the day in Sioux City, Iowa, to workers at a steel plant.

Romney, talking about popular entitlement programs, said until he got into government, "I have to admit I didn't know all the differences" between Medicare, a health insurance program for the elderly, and Medicaid, which helps the poor.

The Democratic National Committee, which is on a daily mission to disrupt Romney's campaign, quickly accused the wealthy former venture capitalist of being out of town with everyday Americans.

"There is not one thing in Mitt Romney's entire history that shows one bit of concern for middle-class Americans," said DNC Chair Debbie Wasserman-Schultz.

Romney told reporters on his plane that he had made a "self-deprecating understatement" and that in his younger days he had done some consulting work for various health care companies.

(Reporting By Steve Holland, editing by Christopher Wilson)

Source: http://us.rd.yahoo.com/dailynews/rss/gop/*http%3A//news.yahoo.com/s/nm/20111217/pl_nm/us_usa_campaign_romney_haley

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Sunday, December 18, 2011

Silence is golden: 'Artist' leads French-y Globes (AP)

BEVERLY HILLS, Calif. ? Ah, Paris. City of Light. Land of romance. Gobbler of all the best Golden Globe nominations.

Presented by overseas reporters based in Hollywood, the Globes may be a worldwide affair, but this time, they have a real French flair. The silent film "The Artist," from French filmmaker Michel Havanavicius, led with six nominations Thursday, while the field includes Woody Allen's French romance "Midnight in Paris" and Martin Scorsese's Paris adventure "Hugo."

Steven Spielberg has two nominees with French connections: the World War I epic "War Horse," set partly in France's countryside, and the animated tale "The Adventures of Tintin," based on comic-book stories created in France's neighbor, Belgium.

"Of course, the foreign press is going to like France," joked Seth Rogen, producer and co-star of the cancer tale "50/50," which has two nominations and no obvious French links.

"War Horse" and "Hugo" are up for best drama, along with two George Clooney films, the Hawaiian family story "The Descendants" and the political thriller "The Ides of March"; the 1960s racial saga "The Help"; and Brad Pitt's baseball tale "Moneyball."

"The Artist," "50/50" and "Midnight in Paris" are competing for the Globes' other best-picture prize ? for a musical or comedy. Also nominated are Kristen Wiig's wedding romp, "Bridesmaids," and Michelle Williams' Marilyn Monroe tale, "My Week with Marilyn."

The Globes help narrow down prospects for the Academy Awards, whose nominations come out Jan. 24. If "The Artist" earns a best-picture nomination then, it will be the first silent movie with a serious shot at Hollywood's top prize since the first year of the Oscars, for 1927-28, when the silent flicks "Wings" and "Sunset" took top honors.

"It's really strange and rare to not hear anything in the theater," said "The Artist" star Jean Dujardin, a dramatic actor nominee for his role as a silent-era superstar whose career capsizes after talking pictures take over in the late 1920s. "It's a new visual and emotional experience for people."

Frenchman Dujardin won the best-actor prize at May's Cannes Film Festival in southern France, where "The Artist" premiered.

Though it has virtually no spoken dialogue, "The Artist" is anything but quiet. The film features clever sound effects and a gorgeous musical score that earned a Globe nomination for French composer Ludovic Bource.

Hazanavicius received directing and screenplay nominations for "The Artist," which also picked up a supporting-actress honor for his wife, Berenice Bejo, who plays a rising star of the sound era.

While the key talent on "The Artist" is French, the film was shot in Hollywood and offers a classy re-creation of the world's film capital in the 1920s and `30s. The supporting cast includes John Goodman, James Cromwell, Penelope Ann Miller and Missi Pyle.

The French connection this year comes heavily from U.S. filmmakers telling stories set in France. Scorsese earned a directing nomination for "Hugo," about an orphan boy living in a Paris train station, where he becomes caught up in a mystery surrounding French film trailblazer Georges Melies. Allen also made the directing cut for "Midnight in Paris," his first film shot entirely in France, the romantic fantasy following an American writer (Owen Wilson) whose nostalgia for the 1920s Paris of Hemingway and Fitzgerald leads him on time-bending adventures.

With a cast that includes French actresses Marion Cotillard and Lea Seydoux and France's first lady, Carla Bruni, "Midnight in Paris" became Allen's biggest hit in decades.

Scorsese also turned nostalgic, crafting a dazzling 3-D Paris of the 1930s and recreating memorable moments from Melies' fantastical silent-film shorts, including "A Trip to the Moon."

"It gave me a chance to work in 3-D, which I've wanted to do since I was young; it allowed me to make a child's adventure, the type of picture that I loved when I was young; and it provided an occasion to pay tribute to one of the cinema's greatest pioneers, Georges Melies," Scorsese said.

Spielberg's "War Horse" follows a resilient steed changing hands among the British, Germans and French during World War I, and his "Adventures of Tintin" chronicles the treasure-seeking exploits of Belgian artist and writer Herge's comic-book hero.

To stretch the Franco angle further, Hollywood exile Roman Polanski, who lives in France after fleeing the United States amid charges he had sex with a 13-year-old girl in 1977, shot his Globe-nominated drama "Carnage" outside of Paris. The film, based on a stage work by French playwright Yasmina Reza, earned musical or comedy actress nominations for Jodie Foster and Kate Winslet as mothers squabbling over their sons' schoolyard fight.

"The Help" and "The Descendants," which tied for second-place behind "The Artist" with five Globe nominations each, are pure American stories.

Adapted from Kathryn Stockett's best-seller, "The Help" earned a dramatic actress honor for Viola Davis and a supporting-actress nomination for Octavia Spencer as Mississippi maids going public with stories about their white employers as the civil-rights movement heats up in the 1960s.

"I'm thrilled for Viola," Spencer said. "I consider myself a rank-and-file actor who's been kicking the can around for 15 years. Viola is a trained Julliard actress who has been doing stage, and now the world is getting to see what she can do."

Co-star Jessica Chastain also had a supporting-actress nomination as Spencer's good-hearted, lonely boss.

"The Descendants" earned a dramatic actor nomination for Clooney as a father struggling to tend his daughters after a boating accident puts his wife in a coma. Shailene Woodley earned a supporting-actress honor as Clooney's troublesome older daughter, while filmmaker Alexander Payne had directing and screenplay nominations.

Multi-tasker Clooney has three nominations. He's also up for directing and screenplay for "The Ides of March." For the acting prize, Clooney will compete against his "Ides" co-star Ryan Gosling, who plays a presidential candidate's aide. Gosling had a second nomination for best musical or comedy actor as a ladies man in the romance "Crazy, Stupid, Love."

Glenn Close also is a dual contender, for best dramatic actress as a woman masquerading as a male butler in the Irish drama "Albert Nobbs" and for best song for writing the lyrics to "Lay Your Head Down," the film's theme tune.

"What an astounding embarrassment of riches," Close said.

Joining Close and Davis in the dramatic actress lineup are: Rooney Mara as a traumatized victim-turned-avenger in "The Girl with the Dragon Tattoo"; Meryl Streep as British Prime Minister Margaret Thatcher in "The Iron Lady"; and Tilda Swinton as a grieving woman coping with her son's terrible deeds in "We Need to Talk About Kevin."

Clooney has another pal in the dramatic actor race, his "Ocean's Eleven" franchise co-star Pitt, who's nominated for his "Moneyball" role as Oakland A's general manager Billy Beane.

Gosling, Clooney and Pitt are up against Leonardo DiCaprio as FBI boss J. Edgar Hoover in "J. Edgar" and Michael Fassbender as a sex addict in "Shame."

Pitt's romantic partner, Angelina Jolie, picked up a nomination for foreign-language film for her directing debut, the Bosnian war drama "In the Land of Blood and Honey."

With drinks and dinner, the Globes are a laid-back affair for Hollywood's elite compared to the Oscars. The show turned a bit prickly last year as host Ricky Gervais repeatedly made sharp wisecracks about stars and the Hollywood Foreign Press Association, a group of about 85 overseas reporters that presents the Globes.

But Gervais helped give the show a TV ratings boost, and he's been invited back as host for a third-straight year.

"The Artist" star Dujardin joked that Gervais must follow the silent-film code if he plans on mocking him, saying "he has to do it silent, without any words."

___

AP Entertainment Writers Sandy Cohen, Derrik J. Lang and Anthony McCartney contributed to this report.

___

Online:

http://www.goldenglobes.org

Source: http://us.rd.yahoo.com/dailynews/rss/movies/*http%3A//news.yahoo.com/s/ap/20111215/ap_en_mo/us_golden_globe_nominations

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Saturday, December 17, 2011

Accused Penn State higher-ups face perjury hearing

FILE -- In a Nov. 7, 2011 file photo former Penn State athletic director Tim Curley, left, and former Penn State Vice President Gary Schultz, right, enter a district judge's office for an arraignment in Harrisburg, Pa. Curley and Schultz have been charged with perjury and failure to report under Pennsylvania?s child protective services law in connection with the investigation into allegations involving former football defensive coordinator Jerry Sandusky, the state attorney general?s office. (AP Photo/Bradley C. Bower/file)

FILE -- In a Nov. 7, 2011 file photo former Penn State athletic director Tim Curley, left, and former Penn State Vice President Gary Schultz, right, enter a district judge's office for an arraignment in Harrisburg, Pa. Curley and Schultz have been charged with perjury and failure to report under Pennsylvania?s child protective services law in connection with the investigation into allegations involving former football defensive coordinator Jerry Sandusky, the state attorney general?s office. (AP Photo/Bradley C. Bower/file)

(AP) ? Two of Penn State's most powerful officials will fight perjury charges and allegations they did not respond properly nine years ago after getting a report a young boy had been sodomized in the football team's showers, and will hear more of the alleged evidence against them Friday in a preliminary hearing to determine if their cases should go to trial.

Gary Schultz and Tim Curley were charged with perjury and failure to report child abuse in early November, on the same day Jerry Sandusky was accused of sexual abuse of eight children.

Schultz was a vice president at the university and had overseen the campus police. Curley was the university's long-serving athletic director. Since they were arrested six weeks ago, Schultz has retired and Curley has been on administrative leave.

The hearing in Dauphin County court in Harrisburg requires the attorney general's office to prove there is a minimum of evidence to support the charges, a relatively low bar and a proceeding that defendants have the right to waive. Sandusky, the school's retired assistant football coach, is charged with 52 criminal counts and a second indictment brought to 10 the number of alleged victims.

Sandusky on Tuesday waived his preliminary hearing at the last minute. His lawyer said he was concerned the proceeding would be too one-sided and that prosecutors had agreed not to seek a bail increase.

The attorneys for Curley and Schultz have not indicated they intend to waive, and even issued a statement earlier this week saying the defendants were looking forward to the preliminary hearing and "to start the process of clearing their good names and demonstrating that they testified truthfully to the grand jury." They declined comment Thursday, but said they would speak with reporters after the hearing.

A key witness Friday could be Mike McQueary, an assistant football coach who the grand jury said told them he saw Sandusky attacking a boy in the shower.

Curley and Schultz gave different accounts, and are charged with not properly alerting law enforcement when McQueary contacted them.

To support the perjury charges, prosecutors must show probable cause the two men lied and that the lies were intentional and material to the case.

"Even though you've had some fairly celebrated folks convicted of perjury, it's a very tough charge to prove," said Temple University law professor Edward Ohlbaum. "You have to have a clear question, an unequivocal answer, and (prove) the defendant knew what he was saying was false."

McQueary's testimony is central to the case, and Sandusky's lawyer and others think he will have to testify Friday. His appearance would mark the first time he has testified in public about what he saw and heard inside the Lasch Football Building.

McQueary told the grand jury he saw Sandusky raping the boy one Friday night before spring break. He said he called his father, then left distraught. He and his father met with coach Joe Paterno the next day.

Paterno, in turn, told his boss, Curley.

Paterno, according to the grand jury report, told Curley that his graduate assistant had seen Sandusky "fondling or doing something of a sexual nature."

Schultz, who oversaw campus security, and Curley met with McQueary 10 days later. McQueary told them that he thought Sandusky had sodomized a young boy, according to his grand jury testimony, which the panel found "extremely credible."

Curley, though, denied that McQueary reported a rape or anything "of a sexual nature whatsoever," the report said. The athletic director described the conduct as "horsing around," the panel said.

Schultz was unsure of what he had been told, but denied the reported conduct included sodomy. He told the grand jury that he was left with "the impression that Sandusky might have inappropriately grabbed the young boy's genitals while wrestling."

The accounts continued to morph, according to the grand jury's outline, when the two university officials spoke to school President Graham Spanier. Spanier testified that he was told Sandusky and a boy "were horsing around in the shower."

Curley, 57, and Schultz, 62, face up to seven years in prison if convicted of perjury. The other charge is a summary offense, less serious than a misdemeanor.

The hearing raises the prospect that Paterno, the 84-year-old campus icon now being treated for lung cancer and a re-fractured pelvis, may be called to the stand. The attorney general's office declined to say who is on its witness list, and it's unclear whether prosecutors could have his grand jury testimony read into the record.

In Pennsylvania, prosecutors must corroborate a lone witness' testimony with either physical evidence or a second person's testimony to meet the probable cause threshold, Ohlbaum said.

Bruce Antkowiak, a former federal prosecutor and defense attorney who now teaches law at St. Vincent College near Latrobe, said he'd bet on McQueary taking the stand.

"If I were the defense, I would be expecting to see McQueary," Antkowiak said. "While some hearsay is permissible, you can't just get up and re-read his grand jury testimony or some other statement into the record."

Charles Porter, a veteran Pittsburgh defense attorney, said the law is that an entire case can't consist of just hearsay evidence at a preliminary hearing.

"To the extent the government has anything else they can offer (as evidence) they could try to just read in his statement into the record," Porter said. "But, the reality in a case like this is, I think he has to take the stand. He appears to be their entire case, as much as I can tell."

No one answered the door at McQueary's home Thursday. His father, John, declined comment to The Associated Press.

McQueary told the grand jury that he happened upon "rhythmic, slapping sounds" in the locker room showers and added that both Sandusky and the boy saw him there, according to a grand jury presentment. Authorities did not know the boy's identity when the report was issued.

McQueary has become a lightning rod in the case, taking heat for not going to the boy's aid or immediately calling police. In a recent email to friends, he went on the defensive, saying he made sure the abuse stopped and went to authorities.

Defense lawyers would no doubt challenge McQueary about his more recent statements. Local and campus police have said they received no such complaint.

Meanwhile, The Patriot-News of Harrisburg has reported that McQueary's story changed when speaking in 2002 to Dr. Jonathan Dranov, a family friend. The newspaper report cited a source said to be familiar with Dranov's testimony.

"If this information is true, and we believe it is, it would be powerful, exculpatory evidence and the charges against our clients should be dismissed," Caroline Roberto, a lawyer for Curley, and Tom Farrell, the attorney representing Schultz, said in their statement.

The Associated Press was unable to reach Dranov this week at his home and office.

___

Associated Press writer Joe Mandak in Pittsburgh contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2011-12-16-Penn%20State-Abuse/id-3a0a3b7a478d4cabaa1ae5abc0ee4fbb

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Friday, December 16, 2011

Khan unanimously approved as owner of Jaguars

Prospective Jacksonville Jaguars owner Shahid Khan is directed to a meeting room in the hotel hosting the NFL owners meeting in Irving, Texas, Wednesday, Dec. 14, 2011. The owners are expected to vote on the sale of the Jaguars to Khan. (AP Photo/LM Otero)

Prospective Jacksonville Jaguars owner Shahid Khan is directed to a meeting room in the hotel hosting the NFL owners meeting in Irving, Texas, Wednesday, Dec. 14, 2011. The owners are expected to vote on the sale of the Jaguars to Khan. (AP Photo/LM Otero)

Prospective Jacksonville Jaguars owner Shahid Khan, right, walks with Eric Grubman, executive vice president of business operations for the NFL, during the NFL owners meeting in Irving, Texas, Wednesday, Dec. 14, 2011. The owners are expected to vote on the sale of the Jaguars to Khan. (AP Photo/LM Otero)

(AP) ? Shahid Khan was 16 when he moved from Pakistan to the United States to attend the University of Illinois. While hanging out in the basement of his fraternity house, he began his American dream of owning an NFL team.

After building a multibillion-dollar company, Khan started working toward spending some of his fortune on fulfilling that college fantasy. He reached out to owners such as Wayne Weaver of the Jacksonville Jaguars to learn the business from the inside, and for them to get to know him.

Khan's dream-turned-plan crossed the goal line Wednesday. He joined the fraternity of NFL owners as his purchase of the Jaguars from Weaver was unanimously approved by the other owners.

The deal is for an estimated $760 million. The ownership transfer will be complete Jan. 4.

"What I want to share with the Jacksonville fans is: Here I am, reporting for duty and ready to serve the fans. Let the fun begin," Khan said with a smile that never left his face during a 20-minute news conference.

The 61-year-old Khan is the league's first minority owner. But that's not the only reason he stands out among his 31 peers. There's also the prominent mustache he's fancied since 1972, a trademark that he joked enables him to leap tall buildings and "do things I didn't know I could do."

Then again, what he's done to get to this point is pretty remarkable.

Upon graduating from college in 1971, Khan went to work at Flex-N-Gate as an engineering manager. He left in 1978 to start his own company, Bumper Works, and two years later bought his former employer. Now his privately held company is a major manufacturer of bumper systems for pickup trucks and sport utility vehicles built in North America. Revenue last year topped $3 billion, and Khan is believed to be a billionaire himself.

He tried buying the St. Louis Rams last year before landing this deal in late November. Now, he's officially part of the NFL's ownership club, starting right away with the other items on the agenda of this long-planned meeting, although he joked "I've got my training wheels on" because the transfer won't be completely official for a few more weeks.

The league's finance committee formally approved Khan's bid last week. So when the agenda item came up Wednesday, there wasn't a single question, or a single dissenting vote.

"I think that's a good sign," NFL Commissioner Roger Goodell said. "It's certainly an endorsement of his ownership."

Cowboys owner Jerry Jones called the Jaguars sale bittersweet because the league is bidding farewell to Weaver. However, Jones praised Khan for his "commitment, his passion and his skill."

"(Weaver) was a real asset to the league, but he did it right and he really brought a very qualified person to the table in Mr. Khan," Jones said. "It takes some skill to come from where he came from to be where he is today. You add that to your (NFL) ownership group, and we've gotten better. ... The more people we can have sitting around those tables in there that have wanted it real bad, that have a paid a high price to get in, and have a vision of how to grow the pie, the better the NFL will be. "

To Jacksonville fans, the biggest questions are his commitment to keeping the team in their city and to turning around a franchise that's struggling in the standings. He made it clear that he's passionate about both.

"This is a partnership, really, with the fans," Khan said. "I am committed obviously to the rebirth, the reinvigoration, doing whatever it takes to put a winner on the field to make Wayne and the other Jacksonvillians proud."

He will be in Jacksonville this weekend to start meeting with fans and sponsors. He and Weaver also will discuss the process of hiring a new coach; Weaver fired Jack Del Rio on Nov. 29, the same day he announced the deal with Khan.

The Jaguars were chosen as an expansion team in 1993 and began playing in 1995. They were a win away from the Super Bowl in their second season, and have made the playoffs five times since, as recently as 2007. They also have hosted a Super Bowl.

"It's been a great 18 years," Weaver said. "But it was the right time. ... I really feel great about handing over the stewardship to Shahid and to finishing the job of bringing a championship to Jacksonville. ... I'm leaving it in good hands."

Associated Press

Source: http://hosted2.ap.org/apdefault/347875155d53465d95cec892aeb06419/Article_2011-12-14-FBN-NFL-Owners/id-1bc40a0fa0e34e3da267c1201be935b5

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Key genetic error found in family of blood cancers

Thursday, December 15, 2011

Scientists have uncovered a critical genetic mutation in some patients with myelodysplastic syndromes ? a group of blood cancers that can progress to a fatal form of leukemia.

The research team at Washington University School of Medicine in St. Louis also found evidence that patients with the mutation are more likely to develop acute leukemia. While this finding needs to be confirmed in additional patients, the study raises the prospect that a genetic test could one day more accurately diagnose the disorder and predict the course of the disease.

The research is available online in Nature Genetics.

The scientists discovered the mutation in a gene known as U2AF1 when they sequenced the entire genome of a 65-year old man with myelodysplastic syndrome that had progressed to leukemia and compared it with the genome of his tumor cells. They also found the genetic error in other patients with myelodysplastic syndromes, an indication of the mutation's significance.

"The mutation in this gene was not on anyone's radar screen," says senior author and hematologist/oncologist Matthew Walter, MD, assistant professor of medicine. "In many cases, the diagnosis of myelodysplastic syndromes is unclear because there isn't a straightforward diagnostic test. By understanding at the genetic level what is contributing to this disease, we hope to eventually improve the diagnosis and treatment of this disorder."

Myelodysplastic syndromes are a difficult-to-treat family of blood cancers that occur when blood cells in the bone marrow don't mature properly. About 28,000 Americans are diagnosed with the disorder each year, most of them over age 60. Drugs are available to treat the disease, but none can cure it.

In about 30 percent of cases, the disorder progresses to a form of acute myeloid leukemia that usually is fatal because chemotherapy drugs are not effective in these patients. Doctors currently assess the likelihood that a patient with myelodysplastic syndrome will develop leukemia by looking at the chromosomes in the tumor cells to determine the extent to which they have broken apart and rearranged themselves, an indicator of the severity of the disease.

"There are chromosomal patterns that indicate high risk and low risk, but the current methods to determine prognosis aren't perfect," says first author Timothy Graubert, MD, associate professor of medicine, who specializes in treating patients with myelodysplastic syndromes.

After identifying the U2AF1 mutation in three patients through whole-genome sequencing, the researchers scoured the gene for the mutation in another 150 patients with myelodysplastic syndromes. They identified the mutation in 13, or nearly 9 percent. The mutations were acquired during development of myelodysplastic syndromes because they were not present in normal cells obtained from each patient.

Patients were almost three times as likely to develop leukemia if they had a mutation in the U2AF1 gene. The disorder progressed to leukemia in 15.2 percent of patients with the mutation, compared with 5.8 percent of those without the genetic error.

The most common mutation results in a single letter change in the DNA at a precise location in the U2AF1 gene. Patients with the genetic error were most likely to have the amino acids phenylalanine or tyrosine substituted for a serine. The researchers say that the mutation by itself does not cause myelodysplastic syndromes but appears to be an early event in the course of the disease.

Normally, the U2AF1 gene makes a protein involved in splicing RNA, a sister molecule of DNA that carries the instructions for building proteins. Splicing brings together different sections of RNA necessary to make a protein and discards those sections that are not needed. The mutated version of the gene still produces a protein, but its splicing activity is altered, which may be important for the development of some cancers.

The new research, funded in part by a federal stimulus grant, adds to a flurry of new findings about the genetic basis of myelodysplastic syndromes. Recent studies in Nature and the New England Journal of Medicine, along with the current study, have identified mutations in a total of eight genes involved in RNA splicing in patients with the disorder.

"Together, these findings are a real game-changer," Graubert says. "A mutation in any one of these eight genes occurs in up to 50 percent of patients with myelodysplastic syndromes. Because these changes are so common, we think there are likely to be implications for improving the diagnosis of the disorder and finding new therapeutic options."

Whole-genome sequencing for cancer was pioneered by scientists at Washington University School of Medicine and the university's Genome Institute, including Richard Wilson, PhD; Elaine Mardis, PhD; Timothy Ley, MD; and Li Ding, PhD, all of whom are co-authors of the study. The new research builds on their work to find novel mutations in cancer by looking across a patient's entire genome.

###

Washington University School of Medicine: http://www.medicine.wustl.edu

Thanks to Washington University School of Medicine for this article.

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Source: http://www.labspaces.net/116060/Key_genetic_error_found_in_family_of_blood_cancers

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Tuesday, December 6, 2011

BofA Merrill unit in $315 million mortgage settlement (Reuters)

(Reuters) ? Bank of America Corp agreed to pay $315 million to settle claims by investors who said they were misled about mortgage securities offerings by its Merrill Lynch unit.

The proposed class-action accord is one of the largest settlements of investor claims against banks over seemingly safe mortgage-backed securities that later proved toxic as credit and housing conditions worsened.

It is also the latest step in Bank of America's efforts to address its legal liabilities stemming from its purchases of Merrill in January 2009 and the mortgage lender Countrywide Financial Corp six months earlier.

Bank of America is based in Charlotte, North Carolina, and is the second-largest U.S. bank by assets.

A Bank of America spokesman did not immediately respond to requests for comment on the settlement. Lawyers for the investors were also not immediately available.

Reuters in mid-November reported the size of the settlement, citing an unnamed source.

The settlement was disclosed publicly late Monday night in court papers filed in U.S. District Court in Manhattan. The settlement requires approval by Judge Jed Rakoff.

The pact resolves claims by investors that Merrill misled them about the risks of $16.5 billion of mortgage-backed securities in 18 offerings made between 2006 and 2007, before Bank of America bought the company. Bank of America did not admit wrongdoing in agreeing to settle.

Investors led by the Public Employees' Retirement System of Mississippi pension fund claimed that offering documents misled them about the quality of the loans backing their investments, and that the loans complied with underwriting guidelines.

They also said the investments did not deserve the investment-grade ratings they once had, being backed by risky loans from such lenders as Countrywide, Merrill's First Franklin Financial unit, and the now-bankrupt IndyMac Bancorp Inc and New Century Financial Corp.

Most of the securities later fell to "junk" status and lost value, the investors said.

The case is separate from litigation over Countrywide mortgage debt being handled by a Los Angeles federal judge.

It is also separate from Bank of America's proposed $8.5 billion settlement with investors in 530 mortgage securitization trusts with $174 billion of unpaid principal. That accord was negotiated by Bank of New York Mellon Corp as trustee.

The case is Public Employees' Retirement System of Mississippi et al v. Merrill Lynch & Co et al, U.S. District Court, Southern District of New York, No. 08-10841.

(Reporting by Jonathan Stempel in New York; Additional reporting by Alison Frankel; Editing by Derek Caney and John Wallace)

Source: http://us.rd.yahoo.com/dailynews/rss/personalfinance/*http%3A//news.yahoo.com/s/nm/20111206/bs_nm/us_bankofamerica_merrill_settlement

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Monday, December 5, 2011

2 critically injured when fans storm Okla. St. field

13 hurt as Cowboys' supporters celebrate school's victory over rival Oklahoma

Image:AP

Emergency medical personnel tend to injured fans under Boone Pickens Stadium following No. 3 Oklahoma State's 44-10 win over No. 13 Oklahoma on Saturday night. Fans were injured during the course of celebrating, which included running onto the field and tearing down goal posts after the victory.

updated 4:13 a.m. ET Dec. 4, 2011

STILLWATER, Okla. - Thousands of fans stormed the field and tore down goalposts after Oklahoma State's 44-10 victory over archrival Oklahoma, leaving at least 13 people injured, including two in critical condition, an emergency medical official said early Sunday.

Michael Authement, who heads the command post at emergency medical provider LifeNet EMS, told The Associated Press that a throng so big took to the field as the game ended that some fans were trampled and one person fell at least 15 feet onto concrete during a wild celebration by Oklahoma State fans.

"They won the game and stormed the field and ripped down the goalposts and some were jumping off the stands and hit the field and others got trampled. It was a nasty deal," Authement said.

He said the crowd was so big it took police at least 45 minutes to clear the crowd from the field at Boone Pickens Stadium in Stillwater.

"There were thousands of people. Thousands of people stormed the field. You couldn't move there were so many people," he added.

Authement said nine ambulances, including six from LifeNet, rushed 11 of the injured away and the two in critical condition were flown to Oklahoma City hospitals. He said he knew of leg fractures but didn't have any details on the extent of the injuries, though two of the 13 had minor injuries and were treated at the scene and released.

An Oklahoma State University police central dispatcher said she had no immediate details to release when contacted by AP and the public information officer did not immediately return messages seeking comment. Stillwater police and the Oklahoma highway patrol also had no immediate comment.

? 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Source: http://nbcsports.msnbc.com/id/45540760/ns/sports-college_football/

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